Stereoselective formal synthesis of crocacin C via Prins cyclization

Yadav, J. S. ; Sridhar Reddy, M. ; Purushothama Rao, P. ; Prasad, A. R. (2007) Stereoselective formal synthesis of crocacin C via Prins cyclization Synlett, 2007 (13). pp. 2049-2052. ISSN 0936-5214

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-2007-984896

Abstract

A formal synthesis of crocacin C is described proving the versatility of Prins cyclization in natural product synthesis. The approach is convergent and highly stereoselective. Cross-metathesis and Heck reactions were utilized for the insertion of an aromatic group in a stereocontrolled manner.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Crocacins; Prins Cyclization; Olefin Rearrangement; Cross-metathesis
ID Code:62949
Deposited On:24 Sep 2011 04:52
Last Modified:24 Sep 2011 04:52

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