Towards the synthesis of pyloricidins: synthesis of (2S,3R,4R,5S)-5-(tert-butyloxy carbonyl)amino-2,3,4,6-tetrahydroxyhexanoyl-β-D-phenylalanine methyl ester

Chandrasekhar, S. ; Nagendra Babu, B. ; Ramakrishna Reddy, N. ; Chandraiah, L. (2005) Towards the synthesis of pyloricidins: synthesis of (2S,3R,4R,5S)-5-(tert-butyloxy carbonyl)amino-2,3,4,6-tetrahydroxyhexanoyl-β-D-phenylalanine methyl ester ARKIVOC: Online Journal of Organic Chemistry, 2005 (11). pp. 40-47. ISSN 1424-6376

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Official URL: http://www.arkat-usa.org/get-file/20117/

Abstract

Highly practical and efficient synthesis of (2S,3R,4R,5S)-5-(tert-butyloxycarbonyl)amino- 2,3,4,6-tetrahydroxyhexanoyl-β-D-phenylalanine methyl ester was achieved using easily available Garner aldehyde and phenylglycine, which is an advanced intermediate for the synthesis of pyloricidins.

Item Type:Article
Source:Copyright of this article belongs to Arkat-USA, Inc..
Keywords:Amino Acids; Antibiotic; Dihydroxylation; Homologation; Debenzylation
ID Code:62880
Deposited On:24 Sep 2011 05:17
Last Modified:24 Sep 2011 05:17

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