Microwave-assisted one-pot synthesis of 2, 4-disubstituted quinolines under solvent-free conditions

Yadav, J. S. ; Reddy, B. V. S. ; Srinivasa Rao, R. ; Naveenkumar, V. ; Nagaiah, K. (2003) Microwave-assisted one-pot synthesis of 2, 4-disubstituted quinolines under solvent-free conditions Synthesis, 2003 (10). pp. 1610-1614. ISSN 0039-7881

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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...

Related URL: http://dx.doi.org/10.1055/s-2003-40531

Abstract

Aromatic imines derived in situ from aryl aldehydes and aryl amines undergo smoothly, cyclization with alkynes on the surface of montmorillonite clay impregnated with copper(I) bromide under solvent-free conditions to produce 2,4-disubstituted quinolines in high yields with excellent selectivity. The reaction rates and yields are significantly improved by employing microwave irradiation.

Item Type:Article
Source:Copyright of this article belongs to Thieme Medical Publishers.
Keywords:Microwave; Aryl Imines; Alkynes; Substituted Quinolines
ID Code:62838
Deposited On:24 Sep 2011 04:44
Last Modified:24 Sep 2011 04:44

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