Total synthesis of (+) Artemisinin

Yadav, J. S. ; Satheesh Babu, R. ; Sabitha, G. (2003) Total synthesis of (+) Artemisinin ARKIVOC: Online Journal of Organic Chemistry, 2003 (3). pp. 125-139. ISSN 1424-6376

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Abstract

(+) Artemisinin is a sesquiterpene endoperoxide lactone with an unprecedented structure is a natural medicine for the treatment of malaria in particular drug against drug resistant malaria and cerebral malaria. The total synthesis of this novel sesquiterpene is described using an inter-molecular radical reaction on important intermediate iodolactone starting from terpene (+) isolimonene.

Item Type:Article
Source:Copyright of this article belongs to Arkat-USA, Inc.
Keywords:Artemisinin; Iodolactone; Selenolactone; Tris(trimethylsilyl)silane
ID Code:62828
Deposited On:24 Sep 2011 04:44
Last Modified:18 May 2016 11:55

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