Three-component reaction of aldose sugars, aryl amines, and 1, 3-diones: a novel synthesis of annulated pyrroles

Yadav, Jhillu S. ; Subba Reddy, Basi V. ; Srinivas, Mende ; Divyavani, Chitteti ; Basha, Shaik Jeelani ; Sarma, Akella V. S. (2008) Three-component reaction of aldose sugars, aryl amines, and 1, 3-diones: a novel synthesis of annulated pyrroles Journal of Organic Chemistry, 73 (8). pp. 3252-3254. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo702012w

Related URL: http://dx.doi.org/10.1021/jo702012w

Abstract

Aldose sugars undergo smooth coupling with enamines, generated in situ from aryl amines and 1,3-diketones, in the presence of 10 mol % of InCl3 in water at 80 °C to furnish annulated pyrrole derivatives in relatively good to high yields. The use of InCl3, in combination with water, makes this procedure quite simple, more convenient, and environmentally friendly.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:62771
Deposited On:24 Sep 2011 05:05
Last Modified:24 Sep 2011 05:05

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