A mild and selective cleavage of tert-butyldimethylsilyl ethers by indium(III) chloride

Yadav, Jhillu S. ; Subba Reddy, Basi V. ; Madan, Chinnala (2000) A mild and selective cleavage of tert-butyldimethylsilyl ethers by indium(III) chloride New Journal of Chemistry (11). pp. 853-854. ISSN 1144-0546

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Official URL: http://xlink.rsc.org/?doi=b004937i

Related URL: http://dx.doi.org/10.1039/B004937I

Abstract

Alkyl tert-butyldimethylsilyl ethers are selectively deprotected to the corresponding alcohols in high yields for the first time by indium(III) chloride in refluxing aqueous acetonitrile. Several functional groups like OBn, Boc, CBz, OBz, O-allyl, OTBDPS, OAc, OMe, ethers, esters and olefins present in the substrate are unaffected.

Item Type:Article
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Deposited On:24 Sep 2011 04:32
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