Total synthesis of 6-epiprelactone-V via a syn-selective oxygen tethered intramolecular Michael reaction

Chandrasekhar, S. ; Rambabu, Ch. ; Jaya Prakash, S. (2006) Total synthesis of 6-epiprelactone-V via a syn-selective oxygen tethered intramolecular Michael reaction Tetrahedron Letters, 47 (7). pp. 1213-1215. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2005.12.012

Abstract

The intramolecular protective group (benzylidene acetal) assisted syn-1,3-diol synthesis has been efficiently utilized in a short synthesis of 6-epiprelactone-V starting from (S)-malic acid.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Keck Allylation; Intramolecular Oxy-Michael Reaction; (−)-Centrolobine; 2, 6-Disubstituted Tetrahydropyran
ID Code:62397
Deposited On:22 Sep 2011 03:28
Last Modified:22 Sep 2011 03:28

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