Chandrasekhar, S. ; Basu, Debjit ; Rambabu, Ch. (2006) Three-component coupling of alkynes, Baylis-Hillman adducts and sodium azide: a new synthesis of substituted triazoles Tetrahedron Letters, 47 (18). pp. 3059-3063. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.03.037
Abstract
A three-component coupling was used to prepare a series of 1,4-disubstituted-1,2,3-triazoles from the corresponding acetylated Baylis-Hillman adducts, sodium azide and terminal alkynes. This one-pot reaction further increases the efficacy of 'Click' synthesis and diversifies the preparation of multi-functional 1,4-disubstituted-1,2,3-triazoles. Graphical abstract A three-component coupling was used to prepare a series of 1,4-disubstituted-1,2,3-triazoles from the corresponding acetylated Baylis-Hillman adducts, sodium azide and terminal alkynes. This one-pot reaction further increases the efficacy of 'Click' synthesis and diversifies the preparation of multi-functional 1,4-disubstituted-1,2,3-triazoles.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Multi-component Coupling; Click Synthesis; Triazoles; Baylis-Hillman Adduct; Terminal Alkynes |
| ID Code: | 62392 |
| Deposited On: | 22 Sep 2011 03:29 |
| Last Modified: | 22 Sep 2011 03:29 |
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