Nucleoside derived amino acids (NDA) in foldamer chemistry: synthesis and conformational studies of homooligomers of modified AZT

Chandrasekhar, S. ; Pavan Kumar Reddy, G. ; Udaya Kiran, M. ; Nagesh, Ch. ; Jagadeesh, B. (2008) Nucleoside derived amino acids (NDA) in foldamer chemistry: synthesis and conformational studies of homooligomers of modified AZT Tetrahedron Letters, 49 (18). pp. 2969-2973. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.03.001

Abstract

Homo short-oligomers of a novel trans-β-amino acid derived from AZT were synthesized and characterized. These adopt right-handed helical turns with their bases positioned systematically along the helix axis. These studies open up new possibilities for synthesizing nucleoside derived functional foldamers.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Trans-β-amino Acid; AZT; Oligonucleoside; NMR; Helical Turn
ID Code:62358
Deposited On:22 Sep 2011 03:33
Last Modified:22 Sep 2011 03:33

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