Hydroxyphthalimide allied triazole-pyrrolidine catalyst for asymmetric Michael additions in water

Chandrasekhar, Srivari ; Pavan Kumar, Togapur ; Haribabu, Kothapalli ; Raji Reddy, Chada (2010) Hydroxyphthalimide allied triazole-pyrrolidine catalyst for asymmetric Michael additions in water Tetrahedron: Asymmetry, 21 (19). pp. 2372-2375. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2010.08.012

Abstract

A new hydroxyphthalimide-coupled triazole-pyrrolidine derivative has been synthesized and demonstrated as an efficient and stereoselective organocatalyst for the asymmetric Michael addition reaction of ketones to nitro olefins at room temperature. Good yields and high selectivities were achieved when benzoic acid was used in combination with organocatalyst 1, employing water as the reaction medium.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:62327
Deposited On:22 Sep 2011 03:38
Last Modified:22 Sep 2011 03:38

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