Nanomechanics of membrane tubulation and DNA assembly

Roopa, T. ; Shivashankar, G. V. (2003) Nanomechanics of membrane tubulation and DNA assembly Applied Physics Letters, 82 (10). pp. 1631-1633. ISSN 0003-6951

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Official URL: http://apl.aip.org/resource/1/applab/v82/i10/p1631...

Related URL: http://dx.doi.org/10.1063/1.1559632

Abstract

We report an interesting regime of tubule formation in multilamellar membrane vesicles. An optically trapped bead is used to apply a localized subpicoNewton force on a cationic vesicle to form a membrane tubule. The force extension curves reveal a saturation phase, with the tubule length extending up to tens of microns, beyond a threshold force 0.6±0.2 pN. We then use the tubule as a sensor for monitoring the dynamics of charge induced DNA integration on cationic membrane vesicles. Our results may also have applications in the development of nanowires and nanofluidic devices.

Item Type:Article
Source:Copyright of this article belongs to American Institute of Physics.
Keywords:Membranes; DNA; Nanowires; Nanotechnology
ID Code:62276
Deposited On:20 Sep 2011 09:36
Last Modified:18 May 2016 11:38

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