Substance P-immunoreactivity in the developing human retinogeniculate pathway

Wadhwa, Shashi ; Rizvi, Tilat A. ; Bijlani, Veena (1988) Substance P-immunoreactivity in the developing human retinogeniculate pathway Neuroscience Letters, 89 (1). pp. 25-30. ISSN 0304-3940

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0304-3940(88)90475-2

Abstract

Substance P has been immunohistochemically localized in the human optic nerves and lateral geniculate nuclei during the prenatal period from 13-14 to 37 weeks of gestation. Substance P-immunoreactive fibres were present in the optic nerves and lateral geniculate nuclei in all these ages thereby providing direct evidence of this undecapeptide being associated with the retinogeniculate pathway. At 16-17 weeks, greater numbers of fibres were observed than in the later ages. It is likely that the reduction in number of optic nerve fibres seen quantitatively during prenatal life may partly be due to the loss of substance P fibres.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Substance P; Retinogeniculate Pathway; Prenatal Life; Human
ID Code:61568
Deposited On:15 Sep 2011 12:48
Last Modified:15 Sep 2011 12:48

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