Hayaran, Archana ; Wadhwa, Shashi ; Bijlani, Veena (1993) Expression of substance P in dentate nucleus of human cerebellum Neuroscience Letters, 152 (1-2). pp. 99-102. ISSN 0304-3940
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0304-3940(93)90493-5
Abstract
The expression of substance P (SP) was examined in dentate nucleus (DN) of human cerebellum. A spatial and temporal sequence was observed in the innervation of the DN. SP appeared at 9-10 weeks and was dense in the dorsomedial region of DN. The SP immunoreactivity continued to increase until 19-21 weeks and showed a decline in the dorsomedial region by 24 weeks. By now, however, the ventrolateral region had a denser innervation. There is thus seemingly a relation between SP innervation and gyri formation in DN. SP-positive fibers were also localized in the neuroepithelium of the IV ventricle at all the ages studied. SP-positive fibers, however, reached the cerebellar cortex only by 24 weeks.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Substance P; Dentate Nucleus; Human; Fetus; Immunohistochemistry |
| ID Code: | 61563 |
| Deposited On: | 15 Sep 2011 12:48 |
| Last Modified: | 15 Sep 2011 12:48 |
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