Pandey, Ganesh ; Kapur, Manmohan (2000) A general strategy towards the synthesis of 1-N-iminosugar type glycosidase inhibitors: demonstration by the synthesis of D- as well as L-glucose type iminosugars (isofagomines) Tetrahedron Letters, 41 (45). pp. 8821-8824. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0040-4039(00)01553-7
Abstract
Both enantiomers of isofagomine, the potent glycosidase inhibitor of a type 1-N-iminosugar have been synthesized by the intramolecular cyclization of the PET generated α-trimethylsilylmethylamine radical cation with the appropriate tethered acetylene moiety.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 61005 |
| Deposited On: | 13 Sep 2011 11:29 |
| Last Modified: | 13 Sep 2011 11:29 |
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