Three-component coupling reactions in ionic liquids: a facile synthesis of α-aminonitriles

Yadav, Jhillu S. ; Reddy, Basi V. S. ; Eshwaraiah, B. ; Srinivas, Mende ; Vishnumurthy, P. (2003) Three-component coupling reactions in ionic liquids: a facile synthesis of α-aminonitriles New Journal of Chemistry, 27 (3). pp. 462-465. ISSN 1144-0546

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Official URL: http://xlink.rsc.org/?doi=b208844b

Related URL: http://dx.doi.org/10.1039/B208844B

Abstract

Aryl imines, derived in situ from aldehydes and amines, smoothly undergo addition with trimethylsilyl cyanide in 1-butyl-3-methylimidazolium tetrafluoroborate or 1-butyl-3-methylimidazolium hexafluorophosphate ionic liquids under mild and neutral reaction conditions to afford the corresponding α-aminonitriles in excellent yields. The ionic liquids can be recycled in five to six runs without any apparent loss of activity.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:60435
Deposited On:09 Sep 2011 03:50
Last Modified:09 Sep 2011 03:50

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