Prevalence of anti-HCV antibodies in Western India

Arankalle, V. A. ; Chadha, M. S. ; Jha, J. ; Amrapurkar, D. N. ; Banerjee, K. (1995) Prevalence of anti-HCV antibodies in Western India Indian Journal of Medical Research, 101 . pp. 91-93. ISSN 0019-5340

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Nearly 2000 serum samples collected from different risk groups from Pune and Bombay metropolitan areas were tested for antibodies to hepatitis C virus (anti-HCV) by Recombinant Immunoblot Assay-3 (RIBA-3). Patients undergoing haemodialysis showed 24.5 per cent seropositivity whereas 5.7 and 5.3 per cent of multiply transfused patients ( > 2 units) and chronic liver disease patients respectively were anti-HCV positive. Leprosy patients had almost 0.7 per cent seropositivity. In other risk groups the positivity rate was nil. In normal population only one out of 830 persons had anti-HCV antibodies. It is therefore apparent that the prevalence of hepatitis C virus (HCV) in western India is not high. However, special care needs to be taken for dialysis patients. As none of the 430 pregnant women and 86 children below the age of 5 yr were anti-HCV positive, vertical mode of HCV transmission seems to be negligible.

Item Type:Article
Source:Copyright of this article belongs to Indian Council of Medical Research.
ID Code:59756
Deposited On:07 Sep 2011 14:33
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