Aetiology of acute sporadic non-A, non-B viral hepatitis in India

Arankalle, V. A. ; Chobe, L. P. ; Jha, J. ; Chadha, M. S. ; Banerjee, K. ; Favorov, M. O. ; Kalinina, T. ; Fields, H. (1993) Aetiology of acute sporadic non-A, non-B viral hepatitis in India Journal of Medical Virology, 40 (2). pp. 121-125. ISSN 0146-6615

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Non-A, non-B (NANB) hepatitis viruses are now classified as hepatitis E (enterically transmitted) and hepatitis C (parenterally transmitted). India experiences a large number of epidemics of the enteric disease every year. In addition, about 70% of the sporadic cases among adults are also due to NANB hepatitis. With the availability of an immunoblot assay for the detection of anti-HEVIgM and the polymerase chain reaction (PCR) for the detection of HCV-RNA, serum samples from epidemic and sporadic NANB patients were screened for these markers. We found that a large number of cases from the epidemics were HEV, though a few remained undiagnosed, while of the sporadic cases only a few could be diagnosed as HCV or HEV; a large proportion remained undiagnosed.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Immunoblot; PCR; Anti-HEVIgM; HCV-RNA
ID Code:59747
Deposited On:07 Sep 2011 14:33
Last Modified:07 Sep 2011 14:33

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