Azido-Schmidt reaction for the formation of amides, imides and lactams from ketones in the presence of FeCl3

Yadav, J. S. ; Subba Reddy, B. V. ; Subba Reddy, U. V. ; Praneeth, K. (2008) Azido-Schmidt reaction for the formation of amides, imides and lactams from ketones in the presence of FeCl3 Tetrahedron Letters, 49 (32). pp. 4742-4745. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.05.113

Abstract

Ketones undergo smooth rearrangement with TMSN3 in the presence of FeCl3 under extremely mild conditions to provide the corresponding amides, imides and lactams in good yields with high selectivity. This method is very useful for the preparation of a wide range of amides, imides and lactams from ketones. The use of FeCl3 makes this method simple, convenient and cost-effective.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Schmidt Reaction; Ketones; Sodium Azide; Amides; Imides and Lactams
ID Code:59662
Deposited On:07 Sep 2011 05:49
Last Modified:07 Sep 2011 05:49

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