Yadav, J. S. ; Bandyopadhyay, A. ; Kunwar, A. C. (2001) An approach towards the C1-C16 fragment of antineoplastic macrolide bryostatins by kinetic resolution of a racemic terminal epoxide using Jacobsen's catalyst Tetrahedron Letters, 42 (29). pp. 4907-4911. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0040-4039(01)00841-3
Abstract
A stereo- and enantioselective approach towards the C1-C16 fragment of bryostatins is reported using Jacobsen's catalyst for kinetic resolution of a terminal epoxide, a Horner-Wadsworth-Emmons coupling reaction and a 1,4-Michael type cyclization as key steps.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Bryostatins; Antitumour Compounds; Coupling Reactions; Michael Reactions |
| ID Code: | 59637 |
| Deposited On: | 07 Sep 2011 05:29 |
| Last Modified: | 07 Sep 2011 05:29 |
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