Enzymatic resolution of N-arylaziridine carboxylates

Sampath Kumar, H. M. ; Shesha Rao, M. ; Pawan Chakravarthy, P. ; Yadav, J. S. (2004) Enzymatic resolution of N-arylaziridine carboxylates Tetrahedron: Asymmetry, 15 (1). pp. 127-130. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2003.10.027

Abstract

N-Arylaziridine-2-carboxylates have been enzymatically resolved using the lipase from Candida rugosa to afford optically active aziridine carboxylates in moderate to high enantiomeric purity. The absolute configuration of the unknown aziridine carboxylates was assigned as S by chemical correlation.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:59611
Deposited On:07 Sep 2011 05:34
Last Modified:07 Sep 2011 05:34

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