Sabitha, Gowravaram ; Kiran Kumar Reddy, G. S. ; Bhaskar Reddy, K. ; Yadav, J. S. (2003) Vanadium(III) chloride catalyzed Biginelli condensation: solution phase library generation of dihydropyrimidin-(2H)-ones Tetrahedron Letters, 44 (34). pp. 6497-6499. ISSN 0040-4039
Full text not available from this repository.
Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0040-4039(03)01564-8
Abstract
The three component condensation of an aldehyde, a β-keto ester and urea (thiourea) in the presence of a catalytic amount of VCl3 is disclosed for the solution phase synthesis of dihydropyrimidinones. The ease of synthesis and work-up allowed the parallel synthesis of a 48-membered library of dihydropyrimidinones quickly and efficiently in good yields.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Biginelli Condensation; VCL3; Dihydropyrimidin-2(1H)-ones; Parallel Synthesis |
| ID Code: | 59602 |
| Deposited On: | 07 Sep 2011 05:34 |
| Last Modified: | 07 Sep 2011 05:34 |
Repository Staff Only: item control page
