Yadav, J. S. ; Subba Reddy, B. V. ; Praneeth, K. (2008) FeCl3-catalyzed alkylation of indoles with 1,3-dicarbonyl compounds: an expedient synthesis of 3-substituted indoles Tetrahedron Letters, 49 (1). pp. 199-202. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.09.166
Abstract
Indoles undergo smooth alkylation at the 3-position with 1,3-dicarbonyl compounds in the presence of 20 mol % of FeCl3 under mild reaction conditions to produce a wide range of 3-substituted indoles in excellent yields and with high E-selectivity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Indoles; Iron(III) Reagents; 1,3-diketones; C-3 Alkylation |
| ID Code: | 59591 |
| Deposited On: | 07 Sep 2011 05:48 |
| Last Modified: | 07 Sep 2011 05:48 |
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