A concise stereoselective total synthesis of (+)-artemisinin

Yadav, J. S. ; Thirupathaiah, B. ; Srihari, P. (2010) A concise stereoselective total synthesis of (+)-artemisinin Tetrahedron, 66 (11). pp. 2005-2009. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tet.2010.01.051

Abstract

A protective group free, concise, and stereoselective total synthesis of (+)-artemisinin, starting from readily available (R)-(+)-citronellal, is described. Asymmetric 1, 4-addition, Aldol condensation, Ene reaction, regioselective hydroboration are the key steps involved in the total synthesis of the target molecule.

Item Type:Article
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ID Code:59555
Deposited On:07 Sep 2011 05:58
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