Formal total synthesis of (−)-salicylihalamides A and B

Yadav, J. S. ; Srihari, P. (2004) Formal total synthesis of (−)-salicylihalamides A and B Tetrahedron: Asymmetry, 15 (1). pp. 81-89. ISSN 0957-4166

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetasy.2003.10.038

Abstract

Formal total synthesis of (−)-salicylihalamides A and B is described starting with a nonracemic chiral epoxide obtained from Jacobsen's kinetic resolution. Sharpless asymmetric epoxidation, Diels Alder reaction, Mitsunobu coupling and ring closing metathesis are the other key steps involved.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:59550
Deposited On:07 Sep 2011 05:34
Last Modified:07 Sep 2011 05:34

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