Kramers-like turnover in load-dependent activated dynamics

Mondal, Debasish ; Ghosh, Pulak Kumr ; Ray, Deb Shankar (2009) Kramers-like turnover in load-dependent activated dynamics The Journal of Chemical Physics, 131 (2). 024110_1-024110_5. ISSN 0021-9606

Full text not available from this repository.

Official URL:

Related URL:


Recent advancement of experimental techniques at the single molecule level has demonstrated how an external load affects a chemical reaction which controls the transport of biological motor proteins. Majority of these studies are concerned with thermodynamically open systems. We have examined a prototype model reaction in terms of inertial Brownian motion of a particle in a force field subjected to an overdamped motion of a viscous load coupled harmonically to the particle. A general analytical expression for the rate constant has been derived to demonstrate that depending on the strength of harmonic coupling and drag coefficient of the load a Kramers-like turnover can be realized in the spatial diffusion-limited regime. The turnover reduces to a crossover between the two states characterized by zero-load and finite load conditions

Item Type:Article
Source:Copyright of this article belongs to American Institute of Physics.
Keywords:Biochemistry; Biodiffusion; Biothermics; Brownian Motion; Molecular Biophysics; Proteins; Reaction Rate Constants
ID Code:59133
Deposited On:03 Sep 2011 12:04
Last Modified:03 Sep 2011 12:04

Repository Staff Only: item control page