Yadav, J. S. ; Subba Reddy, B. V. ; Aravind, S. ; Narayana Kumar, G. G. K. S. ; Madhavi, C. ; Kunwar, A. C. (2008) Three-component, one-pot diastereoselective synthesis of 4-amidotetrahydropyrans via the Prins-Ritter reaction sequence Tetrahedron, 64 (13). pp. 3025-3031. ISSN 0040-4020
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tet.2008.01.038
Abstract
Three-component coupling of carbonyl compounds, homoallylic alcohols, and nitriles has been achieved using 20 mol % of phosphomolybdic acid (PMA) at ambient temperature via the Prins-Ritter sequence to furnish 4-amidotetrahydropyrans in high yields with all cis selectivity. Spirocyclic-4-amidotetrahydropyrans are obtained using cyclic ketones.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Prins-Ritter Sequence; Nitriles; Heteropolyacids; Amidotetrahydropyrans |
| ID Code: | 58908 |
| Deposited On: | 02 Sep 2011 03:30 |
| Last Modified: | 02 Sep 2011 03:30 |
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