A novel TMSI-mediated synthesis of Hantzsch 1,4-dihydropyridines at ambient temperature

Sabitha, Gowravaram ; Kiran Kumar Reddy, G. S. ; Srinivas Reddy, Ch. ; Yadav, J. S. (2003) A novel TMSI-mediated synthesis of Hantzsch 1,4-dihydropyridines at ambient temperature Tetrahedron Letters, 44 (21). pp. 4129-4131. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(03)00813-X

Abstract

The synthesis of various substituted Hantzsch 1,4-dihydropyridines has been achieved using the classical Hantzsch procedure and modified Hantzsch conditions for the first time at room temperature in the presence of iodotrimethylsilane (TMSI) generated in situ in CH3CN, in excellent yields.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:TMSI; Hantzsch 1,4-dihydropyridines; One-pot Condensation; Ambient Temperature
ID Code:58883
Deposited On:02 Sep 2011 03:18
Last Modified:02 Sep 2011 03:18

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