Chemoselective hydrolysis of tert-butyl esters in acetonitrile using molecular iodine as a mild and efficient catalyst

Yadav, J. S. ; Balanarsaiah, E. ; Raghavendra, S. ; Satyanarayana, M. (2006) Chemoselective hydrolysis of tert-butyl esters in acetonitrile using molecular iodine as a mild and efficient catalyst Tetrahedron Letters, 47 (28). pp. 4921-4924. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.05.011

Abstract

A simple, mild and efficient method for the hydrolysis of tert-butyl esters using molecular iodine as a catalyst is described. Acid labile protecting groups, such as N-Boc, OBn, OAc and double bonds, are compatible under the reaction conditions.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Tert-butyl Esters; Tert-butoxycarbonyl; Molecular Iodine; Chemoselective Hydrolysis
ID Code:58870
Deposited On:02 Sep 2011 03:22
Last Modified:02 Sep 2011 03:22

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