Stereoselective total synthesis of (+)-polyrhacitide A

Yadav, J. S. ; Rajendar, G. ; Ganganna, B. ; Srihari, P. (2010) Stereoselective total synthesis of (+)-polyrhacitide A Tetrahedron Letters, 51 (16). pp. 2154-2156. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.02.070

Abstract

A facile stereoselective total synthesis of secondary metabolite (+)-polyrhacitide A is described. Stereoselective aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction are the key steps involved in the target synthesis.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:58848
Deposited On:02 Sep 2011 03:39
Last Modified:02 Sep 2011 03:39

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