Yadav, J. S. ; Subba Reddy, B. V. ; Ramesh, K. ; Narayana Kumar, G. G. K. S. ; Grée, René (2010) A novel aza-Prins-Friedel-Crafts reaction for the synthesis of 4-arylpiperidines Tetrahedron Letters, 51 (5). pp. 818-821. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.12.007
Abstract
Aldehyde, homoallylic amine and arene undergo smooth cyclization in the presence of BF3·OEt2 to afford 4-arylpiperidines in good yields and with high trans-selectivity. This is the first report on the preparation of 4-arylpiperidines via aza-Prins-Friedel-Crafts reaction.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Aza-Prins-Friedel-Crafts Reaction; Arenes; Homoallylic Amines; 4-arylpiperidines |
| ID Code: | 58791 |
| Deposited On: | 02 Sep 2011 03:39 |
| Last Modified: | 02 Sep 2011 03:39 |
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