A convergent approach for the total synthesis of (−)-synrotolide diacetate

Srihari, P. ; Prem Kumar, B. ; Subbarayudu, K. ; Yadav, J. S. (2007) A convergent approach for the total synthesis of (−)-synrotolide diacetate Tetrahedron Letters, 48 (39). pp. 6977-6981. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.07.172

Abstract

A simple carbohydrate based convergent approach towards the total synthesis of (−)-synrotolide diacetate is described employing a Sharpless asymmetric epoxidation, a Grignard assisted lactol opening with a terminal alkyne and a Wittig reaction using the Horner-Emmons reagent as the key steps.

Item Type:Article
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ID Code:58789
Deposited On:02 Sep 2011 03:27
Last Modified:02 Sep 2011 03:27

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