Stereoselective synthesis of basiliskamides A and B via Prins cyclisation

Yadav, J. S. ; Purushothama Rao, P. ; Sridhar Reddy, M. ; Prasad, A. R. (2008) Stereoselective synthesis of basiliskamides A and B via Prins cyclisation Tetrahedron Letters, 49 (37). pp. 5427-5430. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.07.024

Abstract

A stereoselective and convergent approach to basiliskamides A and B is achieved through our recently developed strategy for the construction of polyketide precursors via Prins cyclisation. The approach mainly relies upon reductive opening of 1-iodomethyl cyclic ethers, Mitsunobu inversion, Takai olefination and Stille coupling along with Prins cyclisation.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Natural Products; Prins Cyclisation; Reductive Cleavage; Mitsunobu Inversion and Stille Coupling
ID Code:58766
Deposited On:02 Sep 2011 03:32
Last Modified:02 Sep 2011 03:32

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