Theoretical analysis of conformational possibilities of Z-DNA

Jayaraman, S. ; Yathindra, N. (1980) Theoretical analysis of conformational possibilities of Z-DNA Biochemical and Biophysical Research Communications, 97 (4). pp. 1407-1419. ISSN 0006-291X

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Helical parameter analysis has been carried out to examine various possible forms of Z-type poly(dinucleotide) helices. Use of constraints revealed by experimental findings uniquely characterises the Z-helix and various other forms obtainable by alternative dinucleotide repeat. The results show that the latter forms are characterised by conformational changes either in the 5'-side C4'-C5' bond or 3'-sugar pucker or both in the dinucleotide repeat with concomitant correlated changes in the phosphodiesters linking them.

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ID Code:58707
Deposited On:02 Sep 2011 03:45
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