2Inc/chlorotrimethns ilane: a mild reducing system for the conversion of epoxides into alcohols

Vankar, Yashwant D. ; Arya, Padmashree S. ; Trinadha Rao, C. (1983) 2Inc/chlorotrimethns ilane: a mild reducing system for the conversion of epoxides into alcohols Synthetic Communications, 13 (10). pp. 869-872. ISSN 0039-7911

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Official URL: http://www.tandfonline.com/doi/abs/10.1080/0039791...

Related URL: http://dx.doi.org/10.1080/00397918308063724

Abstract

Reduction of epoxide into the corresponding saturated alcohol is an important synthetic transfornation. Various reagents t o bring about such a conversion have been reported in the literature1. An important aspect of such a transformation is the regioselective opening in case of unsymmetrical epoxides. Numerous modifications of the existing reducing agents have also been reported1 to meet with the regioselective requirements. Every reagent reported so far, to our knowledge, makes use of its hydride donating ability to effect the reduction.

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