External fixators in haemophilia

Lee, V. ; Srivastava, A. ; PalaniKumar, C. ; Daniel, A. J. ; Mathews, V. ; Babu, N. ; Chandy, M. ; Sundararaj, G. D. (2004) External fixators in haemophilia Haemophilia, 10 (1). pp. 52-57. ISSN 1351-8216

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Official URL: http://onlinelibrary.wiley.com/doi/10.1046/j.1365-...

Related URL: http://dx.doi.org/10.1046/j.1365-2516.2003.00844.x


External fixators (EF) are not commonly used for patients with haemophilia. We describe the use of EF (Ilizarov, AO- uni- and bi-planar fixators and Charnley clamp) in nine patients (mean age: 19.2 years; range: 9-37) with haemophilia for the following indications - arthrodesis of infected joints, treatment of open fractures and osteoclasis. EF required an average of nine skin punctures [range: 4-17 were maintained for a period of 15 weeks (range: 8-29.5), without regular factor replacement, till bone healing was adequate and were removed with a single dose of factor infusion]. The mean preoperative factor level achieved was 85% (range: 64-102%). Much lower levels were subsequently maintained till wound healing. The average total factor consumption was 430 IU kg-1 (range: 240-870), administered over a period of 17 days (range: 9-44). There were no major complications related to EF except in a patient who developed inhibitors. In conclusion, EF can be used safely in haemophilic patients who do not have inhibitors and does not require prolonged factor replacement.

Item Type:Article
Source:Copyright of this article belongs to World Federation of Hemophilia.
Keywords:Arthrodesis; External Fixator; Haemophilia; Infected Joint; Open Fracture
ID Code:5827
Deposited On:19 Oct 2010 10:44
Last Modified:28 May 2011 06:33

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