Kumar, Amit ; Rawal, Girish K. ; Vankar, Yashwant D. (2008) Synthesis of hybrids of D-glucose and D-galactose with 1-deoxynojirimycin analogues using ring-closing metathesis Tetrahedron, 64 (10). pp. 2379-2390. ISSN 0040-4020
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tet.2008.01.005
Abstract
Four hybrids of azasugars with D-glucose and D-galactose have been synthesized from 3-nitro-2,3-unsaturated-O-glycosides. All the hybrid molecules showed moderate activity against β-galactosidase, the one derived from D-glucose and 1,4-dideoxygulonojirimycin 18, and 26, which is a hybrid of D-glucose and 1,4-dideoxymannohomonojrimycin, showed selectivity toward α-glucosidase and β-galactosidase, respectively.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | RCM; Diastereoselective Hydroxylation; Stereoselective Nucleophilic Addition |
| ID Code: | 58193 |
| Deposited On: | 31 Aug 2011 06:40 |
| Last Modified: | 31 Aug 2011 06:40 |
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