A convenient protocol for C-H oxidation mediated by an azido radical culminating in Ritter-type amidation

Nair, Vijay ; Suja, T. D. ; Mohanan, Kishor (2005) A convenient protocol for C-H oxidation mediated by an azido radical culminating in Ritter-type amidation Tetrahedron Letters, 46 (18). pp. 3217-3219. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2005.03.048

Abstract

Cerium(IV) ammonium nitrate in combination with sodium azide reacts with unactivated hydrocarbons in acetonitrile to furnish acetamides in one pot. The strategy can be used to introduce nitrogen functionality into a variety of compounds; a carboxylic ester directly afforded the corresponding α-amino acid.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Cerium Ammonium Nitrate; CH Activation; Ritter Reaction; Azides; Radicals
ID Code:58021
Deposited On:31 Aug 2011 12:47
Last Modified:31 Aug 2011 12:47

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