Nair, Vijay ; Rajesh, C. ; Vinod, A. U. ; Bindu, S. ; Sreekanth, A. R. ; Mathen, J. S. ; Balagopal, Lakshmi (2003) Strategies for heterocyclic construction via novel multicomponent reactions based on isocyanides and nucleophilic carbenes Accounts of Chemical Research, 36 (12). pp. 899-907. ISSN 0001-4842
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Official URL: http://pubs.acs.org/doi/abs/10.1021/ar020258p
Related URL: http://dx.doi.org/10.1021/ar020258p
Abstract
This Account focuses mainly on our recent endeavors in the area of multicomponent reactions (MCRs) involving zwitterionic species generated by the addition of isocyanides and nucleophilic carbenes such as dimethoxycarbene and N-heterocyclic carbenes to activated alkynes. The strategy employed encompasses the interception of 1:1 zwitterionic species, generated in situ with a wide range of electrophiles. The new MCRs developed offer an efficient and convenient entry into several heterocycles of biological and synthetic importance.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 58002 |
| Deposited On: | 31 Aug 2011 12:46 |
| Last Modified: | 31 Aug 2011 12:46 |
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