Recovery of preoptic-anterior hypothalamic functions after transplantation

Verma, S. ; Mohan Kumar, V. ; Gopinath, G. ; Sharma, R. ; Tandon, P. N. (1989) Recovery of preoptic-anterior hypothalamic functions after transplantation Restorative Neurology and Neuroscience, 1 (1). pp. 77-81. ISSN 0922-6028

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Kainic acid lesion of the medial preoptic area resulted in the impairment of the thermoregulation and disruption of the reproductive cycle in female rats. The preoptic-anterior hypothalamic area from fetal donor was transplanted into the lesioned area ofthe host. After transplantation, these animals showed signs of estrus cyclicity and a recovery in basal temperature towards normal. They also showed a reduced shift of body temperature on exposure to a hot environment. Thus the female rats, which received transplantation, showed some degree of recovery of functions which were disrupted by kainic acid lesions.

Item Type:Article
Source:Copyright of this article belongs to IOS Press.
Keywords:Preoptic-anterior Hypothalamic Area; Kainic Acid; Female Reproduction; Thermoregulation; Transplantation
ID Code:56876
Deposited On:25 Aug 2011 09:44
Last Modified:10 Jul 2012 06:16

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