Srinivasan, Yogambal ; Ramprasad, M. P. ; Surolia, Avadhesha (1985) Chemical modification studies of gelonin: involvement of arginine residues in biological activity FEBS Letters, 192 (1). pp. 113-118. ISSN 0014-5793
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0014-5793(85)80054-5
Abstract
Gelonin inhibits protein synthesis by inactivating the eukaryotic 60 S ribosomal subunit by an unknown mechanism. The protein was purified in high yield by a new method using Cibacron blue F3GA-Sepharose. Chemical modification studies reveal that arginine residues are essential for biological activity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Ribosome Inactivating Protein; Protein Synthesis; Toxin; Chemical Modification |
| ID Code: | 56453 |
| Deposited On: | 24 Aug 2011 11:26 |
| Last Modified: | 24 Aug 2011 11:26 |
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