Kharbanda, Kusum ; Karak, Asis K. ; Sarkar, Chitra ; Dinda, Amit K. ; Mathur, Meera ; Roy, S. (1993) A sequential cell kinetic study of meningioma cells in primary explant culture using bromodeoxyuridine Journal of Neuro-Oncology, 16 (2). pp. 117-123. ISSN 0167-594X
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Official URL: http://www.springerlink.com/content/l43w3638513516...
Related URL: http://dx.doi.org/10.1007/BF01324698
Abstract
The present study was undertaken to evaluate the sequential BrdU-LI at weekly intervals upto four weeks in 18 primary explant cultures of meningiomas. This revealed three distinct patterns of growth which could be arbitrarily defined as 'degenerating' (group I), 'proliferating' (group II) and 'adaptive' (group III) types. Interestingly two cases of malignant and two of recurrent meningiomas fell into the 'degenerating' group I pattern. The possible explanations for the observed relatively higherin vitro LI values compared to lowerin vivo values as reported in the literature and the theoretical implications of the three distinct patterns of sequential LI values are discussed.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer. |
| Keywords: | Meningioma; Histological Types; Malignant; Recurrent; Primary Cultures; Sequential Labeling Index; Bromodeoxyuridine |
| ID Code: | 56339 |
| Deposited On: | 23 Aug 2011 11:30 |
| Last Modified: | 23 Aug 2011 11:30 |
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