Diterpenoids of Roylea calycina (Roxb.) Briq.

Prakash, Om ; Bhakuni, Dewan S. ; Kapil, Randhir S. ; Subba Rao, G. S. R. ; Ravindranath, Bhagavathula (1979) Diterpenoids of Roylea calycina (Roxb.) Briq. Journal of the Chemical Society, Perkin Transactions 1 . pp. 1305-1308. ISSN 1472-7781

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Official URL: http://pubs.rsc.org/en/content/articlelanding/1979...

Related URL: http://dx.doi.org/10.1039/P19790001305


The structures of three new diterpenes, calyone, calyenone, and precalyone, isolated from the aerial portion of Roylea calycina have been shown to be 3-acetoxy-15,16-epoxy-9-hydroxylabda-1 3(16),14-dien-7-one (2), 3-acetoxy-15,16-epoxylabda-8,13(16),14-trien-7-one (5), and 3-acetoxy-9,13;15,16-diepoxylabda-14-en-7-one (7), respectively, by chemical and spectroscopic studies. Precalyone showed antitumor activity against P-388 lymphocytic leukaemia.

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