Steroid hormones. XXII. Total syntheses of (±)-equilenin methyl ether and (±)-oestrone methyl ether

Birch, A. J. ; Subba Rao, G. S. R. (1970) Steroid hormones. XXII. Total syntheses of (±)-equilenin methyl ether and (±)-oestrone methyl ether Australian Journal of Chemistry, 23 (3). pp. 547-552. ISSN 0004-9425

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Official URL: http://www.publish.csiro.au/?paper=CH9700547

Related URL: http://dx.doi.org/10.1071/CH9700547

Abstract

Total syntheses of oestrone methyl ether and equilenin methyl ether are described, based on the Robinson intermediate (1). The key steps are a stereo-specific introduction of the 18-methyl group and the reduction of ring B of the equilenane skeleton, rendered possible by the presence of an 11-carbonyl.

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Deposited On:19 Aug 2011 03:21
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