Lewis acid catalyzed regioselective ring opening of azetidines with alcohols and thiols

Dwivedi, Sandeep K. ; Gandhi, Shikha ; Rastogi, Namrata ; Singh, Vinod K. (2007) Lewis acid catalyzed regioselective ring opening of azetidines with alcohols and thiols Tetrahedron Letters, 48 (31). pp. 5375-5377. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.06.033

Abstract

An efficient synthesis of amino ethers and amino thioethers has been achieved via the ring cleavage of N-tosylazetidines with alcohols or thiols. The reactions were studied in the presence of various Lewis acids and BF3·OEt2 was found to be the most efficient. The products were obtained in modest to good yields under very mild conditions in 5–15 min.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:55427
Deposited On:18 Aug 2011 08:44
Last Modified:18 Aug 2011 08:44

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