Synthesis of substituted imidazolines via [3+2]-cycloaddition of aziridines with nitriles

Bhanu Prasad, B. A. ; Pandey, Ghanshyam ; Singh, Vinod K. (2004) Synthesis of substituted imidazolines via [3+2]-cycloaddition of aziridines with nitriles Tetrahedron Letters, 45 (6). pp. 1137-1141. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2003.12.015

Abstract

An efficient synthesis of 2,4-disubstituted 1H-imidazolines from aziridines and nitriles in the presence of BF3–Et2O or triethyloxonium tetrafluoroborate has been described. The reaction proceeds via a [3+2]-cycloaddition reaction. Most of the nitriles successfully underwent cycloaddition reactions with aziridines even at room temperature in a very short time.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Aziridine; BF3-Et2O; Triethyloxonium Tetrafluoroborate; [3+2]-cycloaddition; Imidazolines
ID Code:55366
Deposited On:18 Aug 2011 08:39
Last Modified:18 Aug 2011 08:39

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