In vivo sister chromatid exchanges in the euchromatin and constitutive heterochromatin of the Indian mole rat, Nesokia indica

Thelma, B. K. ; Rao, S. R. V. (1982) In vivo sister chromatid exchanges in the euchromatin and constitutive heterochromatin of the Indian mole rat, Nesokia indica Cytogenetics and Cell Genetics, 33 (4). pp. 319-326. ISSN 0301-0171

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Related URL: http://dx.doi.org/10.1159/000131778

Abstract

Distribution of in vivo SCEs in euchromatin and constitutive heterochromatin of Nesokia indica has been studied. The distinct partitioning of the euchromatin and constitutive heterochromatin into different arms of the large X chromosome greatly facilitates such a comparison. The constitutive heterochromatin showed a higher SCE rate per unit length than the total euchromatin. However, between the two types of chromatin in the X itself there was no significant difference. These values were also comparable to that observed for the largest autosome. This study suggests that factor(s) other than chromatin condensation, DNA base composition, and DNA replication kinetics is (are) responsible for the formation of SCEs.

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