Monoclonal antibodies against flagllar antigen of Salmonella typhi

Qadri, Ayub ; Ghash, Souravi ; Upadyay, Shakti ; Talwar, Gurusaran P. (1989) Monoclonal antibodies against flagllar antigen of Salmonella typhi Hybridoma, 8 (3). pp. 353-360. ISSN 0272-457X

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Official URL: http://www.liebertonline.com/doi/abs/10.1089/hyb.1...

Related URL: http://dx.doi.org/10.1089/hyb.1989.8.353

Abstract

Two hybrid cell clones secreting monoclonal antibodies against flagellar antigen isolated from Salmonella typhi, were produced and characterized. The antibodies bound specifically to the flagellar strain of S. typhi and did not show any reactivity with a flagellar S. typhi or with flagellar strains of S. dublin, S. paratyphi A, S. paratyphi B, S. typhimurium, E. coli, Pseudomonas aeruginosa and Klebsiella pneumoniae. The antibodies recognized a determinant present on a group of proteins migrating between 45 Kd and 60 Kd. These monoclonal antibodies would be useful reagents for clinical and epidemiological studies.

Item Type:Article
Source:Copyright of this article belongs to Mary Ann Liebert.
ID Code:52896
Deposited On:04 Aug 2011 09:49
Last Modified:12 Aug 2011 08:35

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