Expression of bcl-2 oncoprotein in Indian oral squamous cell carcinomas

Kannan, K. ; Lakshmi Latha, P. N. ; Shanmugam, G. (1998) Expression of bcl-2 oncoprotein in Indian oral squamous cell carcinomas Oral Oncology, 34 (5). pp. 373-376. ISSN 1368-8375

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Official URL: http://www.oraloncology.com/article/S1368-8375%289...

Abstract

Thirty-nine oral squamous cell carcinomas were assessed for bcl-2 protein expression by immunostaining of tumour sections. Twenty-three per cent of these tumours showed strong nuclear staining for bcl-2 protein. Tumours of the cheek and tongue together accounted for 77% of overexpression of this protein. When bcl-2 expression was compared with p53 expression, they were found to be non-overlapping. These results suggest that overexpression of either of these genes may substitute each other in the development of oral carcinomas of Indians.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Oral Cancer; bcl-2 Expression
ID Code:52733
Deposited On:04 Aug 2011 08:15
Last Modified:04 Aug 2011 08:15

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