Sinha, Sapna ; Panneerselvam, Natarajan ; Shanmugam, Govindaswamy (1995) Genotoxicity of the herbicide butachlor in cultured human lymphocytes Mutation Research: Genetic Toxicology, 344 (1-2). pp. 63-67. ISSN 0165-1218
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0165-1218(95)90039-X
Abstract
Butachlor, a pre-emergence herbicide was investigated for its ability to induce sister chromatid exchanges (SCE) and chromosome aberrations (CA) in cultured human peripheral blood lymphocytes. Mitogen-stimulated lymphocytes were treated with three different concentrations (5, 10 and 20 μg/ml) of butachlor for 24, 48 and 72 h. Our results indicate a dose-dependent increase in the frequency of chromosomal aberrations at 24, 48 and 72 h of treatment with butachlor. No SCE was promoted by butachlor.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Herbicide; Chromosomal Abberation; Sister-chromatid Exchange |
| ID Code: | 52675 |
| Deposited On: | 04 Aug 2011 08:14 |
| Last Modified: | 04 Aug 2011 08:14 |
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