Initiation of the polypeptide chain in the rII B cistron of bacteriophage T4

Sarabhai, Anand ; Lamfrom, Hildegard (1970) Initiation of the polypeptide chain in the rII B cistron of bacteriophage T4 Journal of Molecular Biology, 52 (1). pp. 131-135. ISSN 0022-2836

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0022-2836(70)90183-X

Abstract

The internal initiator x of the rII B cistron of bacteriophage T4 (Sarabhai & Brenner, 1967) can be made to initiate protein synthesis in the absence of a nearby terminating triplet by deleting a particular group of 3n nucleotides to its left. This shows that free ribosomes can directly initiate protein synthesis at an internal initiation sequence, when the initiator is in a structurally favorable configuration.

Item Type:Article
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ID Code:52435
Deposited On:04 Aug 2011 09:32
Last Modified:04 Aug 2011 09:32

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